Alex Ferguson celebrated 25 years as Manchester United's manager as his team beat Sunderland 1-0 at Old Trafford on Saturday although they stayed five points behind Manchester City at the top of the Premier League after City won 3-2 at Queens Park Rangers.
In the other pairings, English champions Manchester United will take on Greek club Olympiakos, while AC Milan take on Atletico Madrid.
Premier League champions Chelsea, beginning to find their form under Guus Hiddink after a shocking start to the season, will face Manchester City in the outstanding tie of the FA Cup fifth round following Sunday's draw.
Manchester City salvaged a point with two late goals to draw 3-3 with Sunderland on Saturday but the result helped tip the balance in the Premier League title race more in Manchester United's favour.
Manchester United have surpassed local rivals Manchester City in the Premier League table in terms of salary paid to their players.
Evergreen Paul Scholes marked his return to Premier League duty with the first goal for Manchester United in a 3-0 home win against Bolton Wanderers as the champions moved level on points with leaders Manchester City on Saturday.
Premier League leaders Manchester City must learn to emulate rivals United in a key department -- winning matches even when playing badly.
Images from the FA Cup semi-final between Crystal Palace and Aston Villa at Wembley stadium, London, on Saturday.
Manchester City striker Sergio Aguero has been banned for three matches after being found guilty of violent conduct, the Football Association said on Friday.
A summary of Saturday's matches in the English Premier League.
Striker Ibrahimovic and defender Rojo are back training with the first team after suffering serious knee ligament injuries last season while midfielder Pogba has shaken off a hamstring problem that has kept him out of the side since September.
Manchester United's troubled season hit a new low on Saturday as Jose Mourinho saw his gamble on introducing a new tactical system backfire with an insipid 3-1 defeat to West Ham United in the Premier League.
The Premier League match between Everton and leaders Manchester City at Goodison Park was halted for around four minutes just before halftime on Tuesday when a male fan handcuffed himself to a goalpost.
Images from the English Premier League matches played across England on Wednesday.
Liverpool ended their seven-year wait for a home league win over Manchester United on Saturday when Ryan Babel came off the bench to give them a deserved 2-1 victory over the champions. Their victory took them to 10 points from four games, the same as Chelsea, who won 3-1 at Manchester City, despite Robinho marking his debut for City with a goal after 13 minutes.
Ryan Giggs enjoyed a dream 900th appearance by scoring a late winner in Manchester United's 2-1 win at Norwich City while Arsenal came from behind to thump Tottenham Hotspur 5-2 in the Premier League on Sunday.
Aston Villa will be the first league visitors to Arsenal's new Emirates Stadium on the opening day of the Premier League.
Arsenal have signed France defender Mikael Silvestre from Manchester United, the London Premier League club said on Wednesday. Silvestre became the first player to move from United to Arsenal in more than 30 years when he agreed a two-year contract with the London club for an undisclosed fee.
British PM Theresa May said the threat level in the country will remain at critical and that 1,000 army troops have been deployed to boost security.
Sporting marked the final home game of coach Ruben Amorim's reign in stunning fashion as Viktor Gyokeres' hat-trick saw them come from behind to thrash Manchester City 4-1 and maintain their superb start to the Champions League on Tuesday.
Like a vulture circling its fallen prey, Manchester United have the scent of another Premier League title in their nostrils with a fifth crown in the last six seasons just two wins away.
Manchester United's title charge was slowed when they drew 0-0 at Newcastle United on Tuesday and missed the chance to move nine points clear of Arsenal at the top of the Premier League standings.
Chelsea enjoyed some much-needed home comfort with goals from Juan Mata and Frank Lampard securing a 2-1 victory over Arsenal in the Premier League on Sunday.
'The price for the big clubs is different for the other clubs. The big historical clubs they are normally punished in the market for their history'
While England boast a formidable attacking threat, there are concerns about their defence which is perhaps why Southgate is prepared to look at new candidates before he has to make his final call for the tournament.
The in-form north London club travel to the Etihad Stadium five points behind Roberto Mancini's City in third place and two behind second-placed Manchester United, who face Arsenal at the Emirates on what could be a pivotal day at the top.
Images from the English Premier League matches played on Wednesday.
Dimitar Berbatov scored both goals on Sunday as Manchester United emerged from the grip of winter to beat Sunderland 2-0 at Old Trafford and consolidate top spot in the Premier League.
Robin van Persie struck twice to earn Manchester United a 2-0 win over Wigan Athletic in the English season's curtain-raising Community Shield at a sun-drenched Wembley on Sunday.
Sergio Aguero opened the floodgates as unbeaten Manchester City thrashed promoted Norwich City 5-1 Saturday to power seven points clear at the top of the Premier League.
'I'm probably one of the only ones that disagrees, for the simple fact that we only had three games that we were below standard.'
Wayne Rooney's hot scoring streak continued on Saturday as he fired Manchester United 10 points clear in the Premier League title race with the only goal in a 1-0 victory at Fulham.
Gabriel Jesus and defender Kyle Walker have tested positive for COVID-19, the Premier League club said on Friday.
Goal-happy Manchester City continued where they left off at Manchester United on Sunday as they came from behind to beat Wolverhampton Wanderers 5-2 on Wednesday to march into the quarter-finals of the League Cup.
If Manchester City really are ready to challenge the Manchester United/Chelsea Premier League hegemony then Wednesday's derby at Eastlands is the time to prove it.
Manchester United return to the scene of their recent domestic humiliation for Wednesday's Champions League game at home to Otelul Galati without captain Nemanja Vidic who has been the tonic easing their recovery.
Manchester United stretched their lead at the top of the Premier League to five points after in-form Antonio Valencia struck nine minutes from time to set up a 2-0 win at relegation-threatened Blackburn Rovers on Monday.
Substitute Michael Owen struck in the sixth minute of injury time to earn Manchester United a 4-3 Premier League win over Manchester City in one of the most dramatic derbies for years on Sunday. Three times United led -- through Wayne Rooney and two Darren Fletcher headers -- but three times City fought back with a goal from Gareth Barry and two from Craig Bellamy, his second coming in the 90th minute, before Owen decided it.
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